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Perturbed Mitochondrial Dynamics Is a Novel Feature of Colitis That Can Be Targeted to Lessen Disease

BACKGROUND & AIMS: Mitochondria exist in a constantly remodelling network, and excessive fragmentation can be pathophysiological. Mitochondrial dysfunction can accompany enteric inflammation, but any contribution of altered mitochondrial dynamics (ie, fission/fusion) to gut inflammation is unkno...

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Detalles Bibliográficos
Autores principales: Mancini, Nicole L., Goudie, Luke, Xu, Warren, Sabouny, Rasha, Rajeev, Sruthi, Wang, Arthur, Esquerre, Nicolas, Al Rajabi, Ala, Jayme, Timothy S., van Tilburg Bernandes, Erik, Nasser, Yasmin, Ferraz, José G.P., Shutt, Timothy, Shearer, Jane, McKay, Derek M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327843/
https://www.ncbi.nlm.nih.gov/pubmed/32298841
http://dx.doi.org/10.1016/j.jcmgh.2020.04.004