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Hydrogen peroxide regulates endothelial surface N-glycoforms to control inflammatory monocyte rolling and adhesion

Monocyte extravasation through the endothelial layer is a hallmark of atherosclerotic plaque development and is mediated by heavily N-glycosylated surface adhesion molecules, such as intercellular adhesion molecule-1 (ICAM-1). N-glycosylation is a key co- and post-translational modification that add...

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Detalles Bibliográficos
Autores principales: McDonald, Kellie R., Hernandez-Nichols, Alexandria L., Barnes, Jarrod W., Patel, Rakesh P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327964/
https://www.ncbi.nlm.nih.gov/pubmed/32171755
http://dx.doi.org/10.1016/j.redox.2020.101498