Repurposing Pathogenic Variants of DMD Gene and its Isoforms for DMD Exon Skipping Intervention

BACKGROUND: Duchenne Muscular Dystrophy (DMD) is a progressive, fatal neuromuscular disorder caused by mutations in the DMD gene. Emerging antisense oligomer based exon skipping therapy provides hope for the restoration of the reading frame. OBJECTIVES: Population-based DMD mutation database may ena...

Descripción completa

Detalles Bibliográficos
Autores principales: Tyagi, Rahul, Kumar, Sumit, Dalal, Ashwin, Mohammed, Faruq, Mohanty, Manju, Kaur, Paramvir, Anand, Akshay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327972/
https://www.ncbi.nlm.nih.gov/pubmed/32655290
http://dx.doi.org/10.2174/1389202920666191107142754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7327972/
https://www.ncbi.nlm.nih.gov/pubmed/32655290
http://dx.doi.org/10.2174/1389202920666191107142754

Ejemplares similares