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The transcription factor E2A drives neural differentiation in pluripotent cells

The intrinsic mechanisms that link extracellular signalling to the onset of neural differentiation are not well understood. In pluripotent mouse cells, BMP blocks entry into the neural lineage via transcriptional upregulation of inhibitor of differentiation (Id) factors. We have previously identifie...

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Detalles Bibliográficos
Autores principales: Rao, Chandrika, Malaguti, Mattias, Mason, John O., Lowell, Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328008/
https://www.ncbi.nlm.nih.gov/pubmed/32487737
http://dx.doi.org/10.1242/dev.184093