RIF1 controls replication initiation and homologous recombination repair in a radiation dose-dependent manner

RIF1 controls both DNA replication timing and the DNA double-strand break (DSB) repair pathway to maintain genome integrity. However, it remains unclear how RIF1 links these two processes following exposure to ionizing radiation (IR). Here, we show that inhibition of homologous recombination repair...

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Detalles Bibliográficos
Autores principales: Saito, Yuichiro, Kobayashi, Junya, Kanemaki, Masato T., Komatsu, Kenshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328141/
https://www.ncbi.nlm.nih.gov/pubmed/32434870
http://dx.doi.org/10.1242/jcs.240036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328141/
https://www.ncbi.nlm.nih.gov/pubmed/32434870
http://dx.doi.org/10.1242/jcs.240036

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