Complete radiological response to first-line regorafenib in a patient with abdominal relapse of BRAF V600E mutated GIST

Up to 13% of KIT and PDGFRA wild-type (WT) gastrointestinal stromal tumours (GIST) harbour a BRAF mutation, mostly involving the exon 15 V600E hot spot. Even if BRAF mutation is recognized as druggable target in other solid tumours, currently advanced BRAF-mutant GIST share the same therapeutical al...

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Detalles Bibliográficos
Autores principales: Nannini, Margherita, Valerio, Di Scioscio, Gruppioni, Elisa, Altimari, Annalisa, Chiusole, Benedetta, Saponara, Maristella, Pantaleo, Maria Abbondanza, Brunello, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328213/
https://www.ncbi.nlm.nih.gov/pubmed/32647535
http://dx.doi.org/10.1177/1756284820927305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328213/
https://www.ncbi.nlm.nih.gov/pubmed/32647535
http://dx.doi.org/10.1177/1756284820927305

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