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Competition between maturation and degradation drives human snRNA 3′ end quality control
Polymerases and exonucleases act on 3′ ends of nascent RNAs to promote their maturation or degradation but how the balance between these activities is controlled to dictate the fates of cellular RNAs remains poorly understood. Here, we identify a central role for the human DEDD deadenylase TOE1 in d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328512/ https://www.ncbi.nlm.nih.gov/pubmed/32499401 http://dx.doi.org/10.1101/gad.336891.120 |