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Twist-dependent ratchet functioning downstream from Dorsal revealed using a light-inducible degron

Graded transcription factors are pivotal regulators of embryonic patterning, but whether their role changes over time is unclear. A light-regulated protein degradation system was used to assay temporal dependence of the transcription factor Dorsal in dorsal–ventral axis patterning of Drosophila embr...

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Detalles Bibliográficos
Autores principales: Irizarry, Jihyun, McGehee, James, Kim, Goheun, Stein, David, Stathopoulos, Angelike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328519/
https://www.ncbi.nlm.nih.gov/pubmed/32467225
http://dx.doi.org/10.1101/gad.338194.120