Cargando…

High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer's disease

Alzheimer's disease (AD), the most common cause of dementia, affects millions of people worldwide. Suggested mechanisms of neurotoxicity in AD include impaired calcium (Ca(2+)) homeostasis and mitochondrial dysfunction, both contributing to neuronal damage. Little was known about the exact mito...

Descripción completa

Detalles Bibliográficos
Autores principales: Calvo-Rodriguez, Maria, Bacskai, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328672/
https://www.ncbi.nlm.nih.gov/pubmed/32656500
http://dx.doi.org/10.15698/cst2020.07.226