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Using liquid chromatography mass spectrometry (LC-MS) to assess the effect of age, high-fat diet, and rat strain on the liver metabolome

The goal of this study was to use liquid chromatography mass spectrometry to assess metabolic changes of two different diets in three distinct rat strains. Sprague-Dawley, Fischer 344, and Brown-Norway male rats were maintained on a high-fat, or regular diet for 24 weeks. Liver tissue was collected...

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Detalles Bibliográficos
Autores principales: Boyce, Greg, Shoeb, Mohammad, Kodali, Vamsi, Meighan, Terence, Roberts, Jenny R., Erdely, Aaron, Kashon, Michael, Antonini, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329071/
https://www.ncbi.nlm.nih.gov/pubmed/32609782
http://dx.doi.org/10.1371/journal.pone.0235338