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Using liquid chromatography mass spectrometry (LC-MS) to assess the effect of age, high-fat diet, and rat strain on the liver metabolome
The goal of this study was to use liquid chromatography mass spectrometry to assess metabolic changes of two different diets in three distinct rat strains. Sprague-Dawley, Fischer 344, and Brown-Norway male rats were maintained on a high-fat, or regular diet for 24 weeks. Liver tissue was collected...
Autores principales: | Boyce, Greg, Shoeb, Mohammad, Kodali, Vamsi, Meighan, Terence, Roberts, Jenny R., Erdely, Aaron, Kashon, Michael, Antonini, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329071/ https://www.ncbi.nlm.nih.gov/pubmed/32609782 http://dx.doi.org/10.1371/journal.pone.0235338 |
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