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Association of smoking habits with TXNIP DNA methylation levels in leukocytes among general Japanese population

Thioredoxin-interacting protein (TXNIP) inhibits the activity of thioredoxin (TXN), leading to increased oxidative stress. Expression of the TXNIP gene is regulated by DNA methylation. However, no study has reported the influence of lifestyle factors on TXNIP DNA methylation. Our goal was to determi...

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Detalles Bibliográficos
Autores principales: Maeda, Keisuke, Yamada, Hiroya, Munetsuna, Eiji, Fujii, Ryosuke, Yamazaki, Mirai, Ando, Yoshitaka, Mizuno, Genki, Ishikawa, Hiroaki, Ohashi, Koji, Tsuboi, Yoshiki, Hashimoto, Shuji, Hamajima, Nobuyuki, Suzuki, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329107/
https://www.ncbi.nlm.nih.gov/pubmed/32609762
http://dx.doi.org/10.1371/journal.pone.0235486