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Mass spectrometry-based absolute quantification of amyloid proteins in pathology tissue specimens: Merits and limitations

To clarify the significance of quantitative analyses of amyloid proteins in clinical practice and in research relating to systemic amyloidoses, we applied mass spectrometry–based quantification by isotope-labeled cell-free products (MS-QBIC) to formalin-fixed, paraffin-embedded (FFPE) tissues. The t...

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Detalles Bibliográficos
Autores principales: Ogawa, Makiko, Shintani-Domoto, Yukako, Nagashima, Yoshiki, Ode, Koji L., Sato, Aya, Shimizu, Yoshihiro, Ohashi, Kenichi, Roehrl, Michael H. A., Ushiku, Tetsuo, Ueda, Hiroki R., Fukayama, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329117/
https://www.ncbi.nlm.nih.gov/pubmed/32609750
http://dx.doi.org/10.1371/journal.pone.0235143