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Esophageal extracellular matrix hydrogel mitigates metaplastic change in a dog model of Barrett’s esophagus

Chronic inflammatory gastric reflux alters the esophageal microenvironment and induces metaplastic transformation of the epithelium, a precancerous condition termed Barrett’s esophagus (BE). The microenvironmental niche, which includes the extracellular matrix (ECM), substantially influences cell ph...

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Detalles Bibliográficos
Autores principales: Naranjo, Juan Diego, Saldin, Lindsey T., Sobieski, Eric, Quijano, Lina M., Hill, Ryan C., Chan, Patrick G., Torres, Crisanto, Dziki, Jenna L., Cramer, Madeline C., Lee, Yoojin C., Das, Rohit, Bajwa, Anant K., Nossair, Rania, Klimak, Molly, Marchal, Lucile, Patel, Shil, Velankar, Sachin S., Hansen, Kirk C., McGrath, Kevin, Badylak, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329334/
https://www.ncbi.nlm.nih.gov/pubmed/32656339
http://dx.doi.org/10.1126/sciadv.aba4526