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A sensitive method for analyzing fluconazole in extremely small volumes of neonatal serum

BACKGROUND: The need for a large volume of serum sample significantly reduces the feasibility of neonatal pharmacokinetic studies in daily practice, which must often rely on scavenged or opportunistic sampling. This problem is most apparent in preterm newborns, where ethical and practical considerat...

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Detalles Bibliográficos
Autores principales: Saito, Jumpei, Tanzawa, Ayano, Kojo, Yuka, Maruyama, Hidehiko, Isayama, Tetsuya, Shoji, Kensuke, Ito, Yushi, Yamatani, Akimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329421/
https://www.ncbi.nlm.nih.gov/pubmed/32626595
http://dx.doi.org/10.1186/s40780-020-00170-y