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Genomic profiling of colorectal cancer with isolated lung metastasis

BACKGROUND: Metastasis is a major cause of failed colorectal cancer (CRC) treatment. While lung metastasis (LM) is observed in 10–15% of patients with CRC, the genetic mechanisms that cause CRC to metastasize to the lung remain unclear. METHODS: In this study, we employed whole exome sequencing (WES...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Di, Jiabo, Wang, Zaozao, Gao, Pin, Jiang, Beihai, Su, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329491/
https://www.ncbi.nlm.nih.gov/pubmed/32624706
http://dx.doi.org/10.1186/s12935-020-01373-x