Knockdown of LAP2α inhibits osteogenic differentiation of human adipose-derived stem cells by activating NF-κB

BACKGROUND: Lamina-associated polypeptide 2α (LAP2α) is a nucleoplasmic protein that has been involved in the regulation of the cell cycle, gene transcription, and adult stem cell function. LAP2α down-regulation is linked to age-related osteoporosis and bone deformities; however, the underlying mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Yiman, Zhang, Xiao, Ge, Wenshu, Zhou, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329510/
https://www.ncbi.nlm.nih.gov/pubmed/32611381
http://dx.doi.org/10.1186/s13287-020-01774-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329510/
https://www.ncbi.nlm.nih.gov/pubmed/32611381
http://dx.doi.org/10.1186/s13287-020-01774-9

Ejemplares similares