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Knockdown of LAP2α inhibits osteogenic differentiation of human adipose-derived stem cells by activating NF-κB
BACKGROUND: Lamina-associated polypeptide 2α (LAP2α) is a nucleoplasmic protein that has been involved in the regulation of the cell cycle, gene transcription, and adult stem cell function. LAP2α down-regulation is linked to age-related osteoporosis and bone deformities; however, the underlying mech...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329510/ https://www.ncbi.nlm.nih.gov/pubmed/32611381 http://dx.doi.org/10.1186/s13287-020-01774-9 |