Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data

BACKGROUND: The traditional approach to studying the epigenetic mechanism CpG methylation in tissue samples is to identify regions of concordant differential methylation spanning multiple CpG sites (differentially methylated regions). Variation limited to single or small numbers of CpGs has been ass...

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Detalles Bibliográficos
Autores principales: Scott, C. Anthony, Duryea, Jack D., MacKay, Harry, Baker, Maria S., Laritsky, Eleonora, Gunasekara, Chathura J., Coarfa, Cristian, Waterland, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329512/
https://www.ncbi.nlm.nih.gov/pubmed/32605651
http://dx.doi.org/10.1186/s13059-020-02065-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329512/
https://www.ncbi.nlm.nih.gov/pubmed/32605651
http://dx.doi.org/10.1186/s13059-020-02065-5

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