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Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data
BACKGROUND: The traditional approach to studying the epigenetic mechanism CpG methylation in tissue samples is to identify regions of concordant differential methylation spanning multiple CpG sites (differentially methylated regions). Variation limited to single or small numbers of CpGs has been ass...
Autores principales: | Scott, C. Anthony, Duryea, Jack D., MacKay, Harry, Baker, Maria S., Laritsky, Eleonora, Gunasekara, Chathura J., Coarfa, Cristian, Waterland, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329512/ https://www.ncbi.nlm.nih.gov/pubmed/32605651 http://dx.doi.org/10.1186/s13059-020-02065-5 |
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