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Chromatin 3D structure reconstruction with consideration of adjacency relationship among genomic loci
BACKGROUND: Chromatin 3D conformation plays important roles in regulating gene or protein functions. High-throughout chromosome conformation capture (3C)-based technologies, such as Hi-C, have been exploited to acquire the contact frequencies among genomic loci at genome-scale. Various computational...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329537/ https://www.ncbi.nlm.nih.gov/pubmed/32611376 http://dx.doi.org/10.1186/s12859-020-03612-4 |