Brief ex vivo Fas-ligand incubation attenuates GvHD without compromising stem cell graft performance

Graft versus host disease (GvHD) remains a limiting factor for successful hematopoietic stem cell transplantation (HSCT). T cells and antigen-presenting cells (APCs) are major components of the hematopoietic G-CSF mobilized peripheral blood cell (MPBC) graft. Here we show that a short incubation (2 ...

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Detalles Bibliográficos
Autores principales: Levy-Barazany, Hilit, Shachnai-Pinkas, Liat, Rodionov, Galina, Saar, Alex, Rosenzwaig, Michal, Gez, Liron, Rodin, Anastasia, Marelly, Nitzan, Abraham, Michal, Mishalian, Inbal, Wildbaum, Hila, Katz, Tamar, Baar, Yuval, Yarkoni, Shai, Bakimer-Kleiner, Ronit, Peled, Amnon, Zuckerman, Tsila, Stein, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329633/
https://www.ncbi.nlm.nih.gov/pubmed/32433499
http://dx.doi.org/10.1038/s41409-020-0941-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329633/
https://www.ncbi.nlm.nih.gov/pubmed/32433499
http://dx.doi.org/10.1038/s41409-020-0941-2

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