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Identification by mass spectrometry and immunoblotting of xenogeneic antigens in the N- and O-glycomes of porcine, bovine and equine heart tissues

Animal bioprosthetic heart valves (BHV) are used to replace defective valves in patients with valvular heart disease. Especially young BHV recipients may experience a structural valve deterioration caused by an immune reaction in which α-Gal and Neu5Gc are potential target antigens. The expression o...

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Detalles Bibliográficos
Autores principales: Jin, Chunsheng, Cherian, Reeja Maria, Liu, Jining, Playà-Albinyana, Heribert, Galli, Cesare, Karlsson, Niclas G., Breimer, Michael E., Holgersson, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329767/
https://www.ncbi.nlm.nih.gov/pubmed/32542517
http://dx.doi.org/10.1007/s10719-020-09931-1