In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug–drug interactions

BACKGROUND: Inhibition of cytochrome P450 (CYP) enzymes is the most common cause of harmful drug–drug interactions. The present study aimed at examining the inhibitory effect of the novel antipsychotic drug asenapine on the main CYP enzymes in human liver. METHODS: The experiments were performed in...

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Detalles Bibliográficos
Autores principales: Wójcikowski, Jacek, Danek, Przemysław J., Basińska-Ziobroń, Agnieszka, Pukło, Renata, Daniel, Władysława A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329795/
https://www.ncbi.nlm.nih.gov/pubmed/32219694
http://dx.doi.org/10.1007/s43440-020-00089-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329795/
https://www.ncbi.nlm.nih.gov/pubmed/32219694
http://dx.doi.org/10.1007/s43440-020-00089-z

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