Desformylflustrabromine, a positive allosteric modulator of α4β2-containing nicotinic acetylcholine receptors, enhances cognition in rats

RATIONALE: The α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) may represent useful targets for cognitive improvement. It has been recently proposed that a strategy based on positive allosteric modulation of α4β2-nAChRs reveals several advantages over the direct agonist approach. Nevertheless,...

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Detalles Bibliográficos
Autores principales: Nikiforuk, Agnieszka, Litwa, Ewa, Krawczyk, Martyna, Popik, Piotr, Arias, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329799/
https://www.ncbi.nlm.nih.gov/pubmed/32207091
http://dx.doi.org/10.1007/s43440-020-00092-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329799/
https://www.ncbi.nlm.nih.gov/pubmed/32207091
http://dx.doi.org/10.1007/s43440-020-00092-4

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