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Desformylflustrabromine, a positive allosteric modulator of α4β2-containing nicotinic acetylcholine receptors, enhances cognition in rats

RATIONALE: The α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) may represent useful targets for cognitive improvement. It has been recently proposed that a strategy based on positive allosteric modulation of α4β2-nAChRs reveals several advantages over the direct agonist approach. Nevertheless,...

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Detalles Bibliográficos
Autores principales:	Nikiforuk, Agnieszka, Litwa, Ewa, Krawczyk, Martyna, Popik, Piotr, Arias, Hugo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329799/ https://www.ncbi.nlm.nih.gov/pubmed/32207091 http://dx.doi.org/10.1007/s43440-020-00092-4

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