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Potential antipsychotic action of the selective agonist of adenosine A1 receptors, 5′-Cl-5′-deoxy-ENBA, in amphetamine and MK-801 rat models

BACKGROUND: Disturbances of dopaminergic and glutamatergic transmissions have been suggested to be involved in the pathomechanisms underlying psychotic symptoms of schizophrenia. In line with this concept, hyperlocomotion induced by the dopaminomimetic amphetamine and the uncompetitive antagonist of...

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Detalles Bibliográficos
Autores principales: Ossowska, Krystyna, Kosmowska, Barbara, Wardas, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329802/
https://www.ncbi.nlm.nih.gov/pubmed/32219695
http://dx.doi.org/10.1007/s43440-020-00093-3