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Cystathionine β-synthase deficiency: different changes in proteomes of thrombosis-resistant Cbs(−/−) mice and thrombosis-prone CBS(−/−) humans
Cystathionine β-synthase (CBS)-deficient patients are prone to vascular thrombosis. In contrast, Cbs(−/−) mice show no abnormalities in blood coagulation. To identify molecular basis underlying these disparately different thrombotic phenotypes, we analyzed plasma proteomes of Cbs(−/−) vs. Cbs(+/+) m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329814/ https://www.ncbi.nlm.nih.gov/pubmed/32612202 http://dx.doi.org/10.1038/s41598-020-67672-5 |