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Disorganization of chondrocyte columns in the growth plate does not aggravate experimental osteoarthritis in mice

Osteoarthritis (OA) is a multifactorial joint disease mainly affecting articular cartilage (AC) with a relevant biomechanical component. During endochondral ossification growth plate (GP) chondrocytes arrange in columns. GPs do not ossify in skeletally mature rodents. In neonatal mice, an altered jo...

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Detalles Bibliográficos
Autores principales: Lamuedra, Ana, Gratal, Paula, Calatrava, Lucía, Ruiz-Perez, Víctor Luis, Largo, Raquel, Herrero-Beaumont, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329885/
https://www.ncbi.nlm.nih.gov/pubmed/32612184
http://dx.doi.org/10.1038/s41598-020-67518-0