Inhibition of mTOR via an AAV-Delivered shRNA Tested in a Rat OIR Model as a Potential Antiangiogenic Gene Therapy

PURPOSE: Recent studies have shown that inhibitors of the mechanistic target of rapamycin (mTOR) play important roles in proliferating endothelial cells within the retinal vasculature. Here we explore the effects of inhibiting mTOR as a potential gene therapeutic against pathological retinal angioge...

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Detalles Bibliográficos
Autores principales: Lee, Steven Hyun Seung, Chang, HeeSoon, Kim, Ji Hyun, Kim, Hee Jong, Choi, Jun-Sub, Chung, Sunho, Woo, Ha-Na, Lee, Kyoung Jin, Park, Keerang, Lee, Joo Yong, Lee, Heuiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329967/
https://www.ncbi.nlm.nih.gov/pubmed/32106292
http://dx.doi.org/10.1167/iovs.61.2.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329967/
https://www.ncbi.nlm.nih.gov/pubmed/32106292
http://dx.doi.org/10.1167/iovs.61.2.45

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