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Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency

Germ cell depletion in recipient testes is indispensable for successful transplantation of spermatogonial stem cells. However, we found that such treatment had an adverse effect on spermatogenesis of orthotopically transplanted donor testis tissues. In the donor tissue, the frequency of stimulated b...

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Detalles Bibliográficos
Autores principales: Tsuchimoto, Akihiro, Tone, Masaaki, Ogonuki, Narumi, Hada, Masashi, Ogura, Atsuo, Takashima, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330030/
https://www.ncbi.nlm.nih.gov/pubmed/32612133
http://dx.doi.org/10.1038/s41598-020-67595-1