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Germ cell depletion in recipient testis has adverse effects on spermatogenesis in orthotopically transplanted testis pieces via retinoic acid insufficiency
Germ cell depletion in recipient testes is indispensable for successful transplantation of spermatogonial stem cells. However, we found that such treatment had an adverse effect on spermatogenesis of orthotopically transplanted donor testis tissues. In the donor tissue, the frequency of stimulated b...
Autores principales: | Tsuchimoto, Akihiro, Tone, Masaaki, Ogonuki, Narumi, Hada, Masashi, Ogura, Atsuo, Takashima, Seiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330030/ https://www.ncbi.nlm.nih.gov/pubmed/32612133 http://dx.doi.org/10.1038/s41598-020-67595-1 |
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