Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer’s disease model by increasing the expression of microRNA-146a in hippocampus

Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β and tau. We previously reported that administration of bone marrow mesenchymal stem cells (BM-MSCs) ameliorates diabetes-induced cognitive impairment by transferring exosomes derived from these cells into astrocytes. Here, we...

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Detalles Bibliográficos
Autores principales: Nakano, Masako, Kubota, Kenta, Kobayashi, Eiji, Chikenji, Takako S., Saito, Yuki, Konari, Naoto, Fujimiya, Mineko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330036/
https://www.ncbi.nlm.nih.gov/pubmed/32612165
http://dx.doi.org/10.1038/s41598-020-67460-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330036/
https://www.ncbi.nlm.nih.gov/pubmed/32612165
http://dx.doi.org/10.1038/s41598-020-67460-1

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