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Genome-wide investigation of gene-cancer associations for the prediction of novel therapeutic targets in oncology
A major cause of failed drug discovery programs is suboptimal target selection, resulting in the development of drug candidates that are potent inhibitors, but ineffective at treating the disease. In the genomics era, the availability of large biomedical datasets with genome-wide readouts has the po...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330039/ https://www.ncbi.nlm.nih.gov/pubmed/32612205 http://dx.doi.org/10.1038/s41598-020-67846-1 |