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Flexible experimental designs for valid single-cell RNA-sequencing experiments allowing batch effects correction
Despite their widespread applications, single-cell RNA-sequencing (scRNA-seq) experiments are still plagued by batch effects and dropout events. Although the completely randomized experimental design has frequently been advocated to control for batch effects, it is rarely implemented in real applica...
Autores principales: | Song, Fangda, Chan, Ga Ming Angus, Wei, Yingying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330047/ https://www.ncbi.nlm.nih.gov/pubmed/32612268 http://dx.doi.org/10.1038/s41467-020-16905-2 |
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