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Alpha-Lipoic Acid Mediates Clearance of Iron Accumulation by Regulating Iron Metabolism in a Parkinson’s Disease Model Induced by 6-OHDA

The disruption of neuronal iron homeostasis and oxidative stress are related to the pathogenesis of Parkinson’s disease (PD). Alpha-lipoic acid (ALA) is a naturally occurring enzyme cofactor with antioxidant and iron chelator properties and has many known effects. ALA has neuroprotective effects on...

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Detalles Bibliográficos
Autores principales: Tai, Shengyan, Zheng, Qian, Zhai, Suzhen, Cai, Ting, Xu, Li, Yang, Lizhu, Jiao, Ling, Zhang, Chunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330090/
https://www.ncbi.nlm.nih.gov/pubmed/32670009
http://dx.doi.org/10.3389/fnins.2020.00612