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An Inverse Relationship Between c-Kit/CD117 and mTOR Confers NK Cell Dysregulation Late After Severe Injury

Major trauma-induced tissue injury causes a dysregulation of the immune system. Severe systemic inflammation occurs early after the insult. Later on, an enhanced risk for life-threatening opportunistic infections develops that culminates at the end of the first week after trauma. CD56(bright) Natura...

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Detalles Bibliográficos
Autores principales: Bösken, Björn, Hepner-Schefczyk, Monika, Vonderhagen, Sonja, Dudda, Marcel, Flohé, Stefanie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330140/
https://www.ncbi.nlm.nih.gov/pubmed/32670280
http://dx.doi.org/10.3389/fimmu.2020.01200