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Endobronchial ultrasound-guided injection of NBTXR3 radio-enhancing nanoparticles into mediastinal and hilar lymph nodes: a swine model to evaluate feasibility, injection technique, safety, nanoparticle retention and dispersion

BACKGROUND: Loco-regionally advanced lung cancer is typically treated with a combination of chemotherapy and radiation therapy, but overall survival and local control remain poor. Radio-enhancing nanoparticles such as NBTXR3 activated by radiotherapy results in increased cell death and potentially a...

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Detalles Bibliográficos
Autores principales: Casal, Roberto F., Schwalk, Audra J., Fowlkes, Natalie, Aburto, Rebeca Romero, Norton, William, Dixon, Katherine A., Lin, Steven, Shaitelman, Simona F., Chintalapani, Gouthami, Hill, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330297/
https://www.ncbi.nlm.nih.gov/pubmed/32642136
http://dx.doi.org/10.21037/jtd.2020.03.100