Silencing of the long non-coding RNA MEG3 suppresses the apoptosis of aortic endothelial cells in mice with chronic intermittent hypoxia via downregulation of HIF-1α by competitively binding to microRNA-135a

BACKGROUND: Chronic intermittent hypoxia (CIH) involves substantial cortico-hippocampal injury, causing impairments of neurocognitive, respiratory, and cardiovascular functions. Long non-coding RNAs (lncRNAs) participate in CIH functions and development. Therefore, we explored the mechanisms involvi...

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Detalles Bibliográficos
Autores principales: Ding, Haibo, Huang, Jiefeng, Wu, Dawen, Zhao, Jianming, Huang, Jianchai, Lin, Qichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330306/
https://www.ncbi.nlm.nih.gov/pubmed/32642094
http://dx.doi.org/10.21037/jtd-19-2472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330306/
https://www.ncbi.nlm.nih.gov/pubmed/32642094
http://dx.doi.org/10.21037/jtd-19-2472

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