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Mechanisms of resistance to osimertinib

The introduction of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) has significantly improved the prognosis of advanced non-small cell lung cancer (NSCLC) patients with EGFR mutations. The most common mechanism of acquired resistance to first- and second-generation EGFR TKIs...

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Detalles Bibliográficos
Autores principales: Lazzari, Chiara, Gregorc, Vanesa, Karachaliou, Niki, Rosell, Rafael, Santarpia, Mariacarmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330330/
https://www.ncbi.nlm.nih.gov/pubmed/32642198
http://dx.doi.org/10.21037/jtd.2019.08.30