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Statistical methods for SNP heritability estimation and partition: A review

In GWAS studies, SNP heritability measures the proportion of phenotypic variance explained by all measured SNPs. Accurate estimation of SNP heritability can help us better understand the degree to which measured genetic variants influence phenotypes. Over the last decade, a variety of statistical me...

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Detalles Bibliográficos
Autores principales: Zhu, Huanhuan, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330487/
https://www.ncbi.nlm.nih.gov/pubmed/32637052
http://dx.doi.org/10.1016/j.csbj.2020.06.011