Harnessing adenosine A2A receptors as a strategy for suppressing the lung inflammation and thrombotic complications of COVID-19: Potential of pentoxifylline and dipyridamole

Counterproductive lung inflammation and dysregulated thrombosis contribute importantly to the lethality of advanced COVID-19. Adenosine A2A receptors (A2AR), expressed by a wide range of immune cells, as well as endothelial cells and platelets, exert cAMP-mediated anti-inflammatory and anti-thrombot...

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Detalles Bibliográficos
Autores principales: DiNicolantonio, James J., Barroso-Aranda, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330590/
https://www.ncbi.nlm.nih.gov/pubmed/32650197
http://dx.doi.org/10.1016/j.mehy.2020.110051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330590/
https://www.ncbi.nlm.nih.gov/pubmed/32650197
http://dx.doi.org/10.1016/j.mehy.2020.110051

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