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Local SDF-1α application enhances the therapeutic efficacy of BMSCs transplantation in osteoporotic bone healing

Bone defect healing is markedly impaired in osteoporotic patient due to poor bone regeneration ability. Stromal cell derived factor-1α (SDF-1α) plays a pivotal role in the repair of various injured tissues including bone. Here, we definite that SDF-1α hydrogels potentiates in vivo osteogenesis of bo...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Wen, Yi, Qiu, Jun, Zhang, Zhaoyichun, Jin, Zuolin, Cao, Meng, Jiao, Yang, Yang, Hongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330617/
https://www.ncbi.nlm.nih.gov/pubmed/32637715
http://dx.doi.org/10.1016/j.heliyon.2020.e04347