EGFRvIII-specific CAR-T cells produced by piggyBac transposon exhibit efficient growth suppression against hepatocellular carcinoma

Adoptive cellular immunotherapy employing chimeric antigen receptors-modified T (CAR-T) cells has demonstrated promising antitumor effects in hematologic cancers. However, CAR-T therapy confront many challenges in solid tumors like immunosuppressive microenvironment, molecular heterogeneity, etc. Th...

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Detalles Bibliográficos
Autores principales: Ma, Yuan, Chen, Yan, Yan, Lei, Cao, Hui-Xia, Han, Shuang-Yin, Cui, Jun-Jun, Wen, Jian Guo, Zheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330669/
https://www.ncbi.nlm.nih.gov/pubmed/32624697
http://dx.doi.org/10.7150/ijms.45603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330669/
https://www.ncbi.nlm.nih.gov/pubmed/32624697
http://dx.doi.org/10.7150/ijms.45603

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