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NK homeobox 2.2 functions as tumor suppressor in colorectal cancer due to DNA methylation

Aim: The role of NK homeobox 2.2 (NKX2.2) in human colorectal cancer (CRC) remains to be unveiled. This study was designed to explore the epigenetic regulation and function of NKX2.2 in human CRC. Methods: The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets were used to assess...

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Detalles Bibliográficos
Autores principales: He, Yuan, Liu, Xiao-Yun, Gong, Rui, Peng, Kun-Wei, Liu, Rong-Bin, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330694/
https://www.ncbi.nlm.nih.gov/pubmed/32626526
http://dx.doi.org/10.7150/jca.43665