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Targeting Sphingosine Kinase by ABC294640 against Diffuse Intrinsic Pontine Glioma (DIPG)

As a highly aggressive pediatric brainstem tumor, diffuse intrinsic pontine glioma (DIPG) accounts for 10% to 20% of childhood brain tumors. The survival rate for DIPG remains very low, with a median survival time as less than one year even under radiotherapy, the current standard treatment. Moreove...

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Detalles Bibliográficos
Autores principales: Dai, Lu, Chen, Jungang, Lin, Zhen, Wang, Zhaoxiong, Mu, Shengyu, Qin, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330698/
https://www.ncbi.nlm.nih.gov/pubmed/32626514
http://dx.doi.org/10.7150/jca.46269