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Detection of TP53 Clonal Variants in Papanicolaou Test Samples Collected up to 6 Years Prior to High-Grade Serous Epithelial Ovarian Cancer Diagnosis

IMPORTANCE: The low 5-year survival rate of women with high-grade serous epithelial ovarian cancer (HGS-EOC) is related to its late diagnosis; thus, improvement in diagnosis constitutes a crucial step to increase the curability of this disease. OBJECTIVE: To determine whether the presence of the clo...

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Detalles Bibliográficos
Autores principales: Paracchini, Lara, Pesenti, Chiara, Delle Marchette, Martina, Beltrame, Luca, Bianchi, Tommaso, Grassi, Tommaso, Buda, Alessandro, Landoni, Fabio, Ceppi, Lorenzo, Bosetti, Cristina, Paderno, Mariachiara, Adorni, Marco, Vicini, Debora, Perego, Patrizia, Leone, Biagio Eugenio, D’Incalci, Maurizio, Marchini, Sergio, Fruscio, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330718/
https://www.ncbi.nlm.nih.gov/pubmed/32609349
http://dx.doi.org/10.1001/jamanetworkopen.2020.7566