Association of a Polygenic Risk Score With Breast Cancer Among Women Carriers of High- and Moderate-Risk Breast Cancer Genes

IMPORTANCE: To date, few studies have examined the extent to which polygenic single-nucleotide variation (SNV) (formerly single-nucleotide polymorphism) scores modify risk for carriers of pathogenic variants (PVs) in breast cancer susceptibility genes. In previous reports, polygenic risk modificatio...

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Detalles Bibliográficos
Autores principales: Gallagher, Shannon, Hughes, Elisha, Wagner, Susanne, Tshiaba, Placede, Rosenthal, Eric, Roa, Benjamin B., Kurian, Allison W., Domchek, Susan M., Garber, Judy, Lancaster, Johnathan, Weitzel, Jeffrey N., Gutin, Alexander, Lanchbury, Jerry S., Robson, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330720/
https://www.ncbi.nlm.nih.gov/pubmed/32609350
http://dx.doi.org/10.1001/jamanetworkopen.2020.8501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330720/
https://www.ncbi.nlm.nih.gov/pubmed/32609350
http://dx.doi.org/10.1001/jamanetworkopen.2020.8501

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