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Decreased Neuronal Excitability in Medial Prefrontal Cortex during Morphine Withdrawal is associated with enhanced SK channel activity and upregulation of small GTPase Rac1
Rationale: Neuroadaptations in the medial prefrontal cortex (mPFC) and Nucleus Accumbens (NAc) play a role in the disruption of control-reward circuits in opioid addiction. Small Conductance Calcium-Activated Potassium (SK) channels in the mPFC have been implicated in neuronal excitability changes d...
Автори: | , , , , , , , , , , , , , , , , |
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Формат: | Online Стаття Текст |
Мова: | English |
Опубліковано: |
Ivyspring International Publisher
2020
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Предмети: | |
Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330845/ https://www.ncbi.nlm.nih.gov/pubmed/32641997 http://dx.doi.org/10.7150/thno.44893 |