Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes

Disturbed renal lipid metabolism, especially cholesterol dysregulation plays a crucial role in the pathogenesis of chronic kidney disease (CKD). We recently reported that angiotensin (Ang) II could induce cholesterol accumulation and injury in podocytes. However, the underlying mechanisms for these...

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Detalles Bibliográficos
Autores principales: Yang, Qian, Hu, Jijia, Yang, Yingjie, Chen, Zhaowei, Feng, Jun, Zhu, Zijing, Wang, Huiming, Yang, Dingping, Liang, Wei, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330847/
https://www.ncbi.nlm.nih.gov/pubmed/32642006
http://dx.doi.org/10.7150/thno.45003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330847/
https://www.ncbi.nlm.nih.gov/pubmed/32642006
http://dx.doi.org/10.7150/thno.45003

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